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Identification of Protein Substrates of Specific PARP Enzymes Using Analog-Sensitive PARP Mutants and a ‘Clickable’ NAD(+) Analog
The PARP family of ADP-ribosyl transferases contains 17 members in human cells, most of which catalyze the transfer of the ADP-ribose moiety of NAD(+) onto their target proteins. This post-translational modification plays important roles in cellular signaling, especially during cellular stresses, su...
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| Publicat a: | Methods Mol Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6465536/ https://ncbi.nlm.nih.gov/pubmed/28695507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6993-7_9 |
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