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Identifying Genomic Sites of ADP-Ribosylation Mediated by Specific Nuclear PARP Enzymes Using Click-ChIP

Nuclear poly(ADP-ribose) polymerases (PARPs), including PARPs 1, 2, 3, and the Tankyrases, belong to a family of enzymes that can bind to chromatin, and covalently modify histones and chromatin-associated proteins with ADP-ribose derived from nuclear NAD(+). The genomic loci where the nuclear PARPs...

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書目詳細資料
發表在:Methods Mol Biol
Main Authors: Rogge, Ryan A., Gibson, Bryan A., Kraus, W. Lee
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465533/
https://ncbi.nlm.nih.gov/pubmed/30097881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8588-3_25
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