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Identifying Genomic Sites of ADP-Ribosylation Mediated by Specific Nuclear PARP Enzymes Using Click-ChIP
Nuclear poly(ADP-ribose) polymerases (PARPs), including PARPs 1, 2, 3, and the Tankyrases, belong to a family of enzymes that can bind to chromatin, and covalently modify histones and chromatin-associated proteins with ADP-ribose derived from nuclear NAD(+). The genomic loci where the nuclear PARPs...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6465533/ https://ncbi.nlm.nih.gov/pubmed/30097881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8588-3_25 |
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