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Excision of Oxidatively Generated Guanine Lesions by Competing Base and Nucleotide Excision Repair Mechanisms in Human Cells

The interchange between different repair mechanisms in human cells has long been a subject of interest. Here, we provide a direct demonstration that the oxidatively generated guanine lesions spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh) embedded in double-stranded DNA, are substrates of b...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chem Res Toxicol
Päätekijät: Shafirovich, Vladimir, Kropachev, Konstantin, Kolbanovskiy, Marina, Geacintov, Nicholas E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465092/
https://ncbi.nlm.nih.gov/pubmed/30688445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00411
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