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Remarkable Enhancement of Nucleotide Excision Repair of a Bulky Guanine Lesion in a Covalently Closed Circular DNA Plasmid Relative to the Same Linearized Plasmid
The excision of DNA lesions by human Nucleotide Excision Repair (NER) has been extensively studied in human cell extracts. Employing DNA duplexes less than 200 base pairs (bp) in lengths containing single bulky, benzo[a]pyrene-derived guanine lesion (B[a]P-dG), the NER yields are typically of the or...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7444659/ https://ncbi.nlm.nih.gov/pubmed/32786887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00441 |
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