Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the CDK4-cyclin D complex

Senescence is a tumor suppressor program characterized by a stable growth arrest while maintaining cell viability. Senescence-associated ribogenesis defects (SARD) have been shown to regulate senescence through the ability of the ribosomal protein S14 (RPS14 or uS11) to bind and inhibit the cyclin-d...

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Bibliographic Details
Published in:Cell Cycle
Main Authors: Del Toro, Neylen, Fernandez-Ruiz, Ana, Mignacca, Lian, Kalegari, Paloma, Rowell, Marie-Camille, Igelmann, Sebastian, Saint-Germain, Emmanuelle, Benfdil, Mehdi, Lopes-Paciencia, Stéphane, Brakier-Gingras, Léa, Bourdeau, Véronique, Ferbeyre, Gerardo, Lessard, Frédéric
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464582/
https://ncbi.nlm.nih.gov/pubmed/30874462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1593708
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