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SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes
The mechanism by which p53 suppresses tumorigenesis remains poorly understood. In the context of aberrant activation of the JAK/STAT5 pathway, SOCS1 is required for p53 activation and the regulation of cellular senescence. In order to identify p53 target genes acting during the senescence response t...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5680560/ https://ncbi.nlm.nih.gov/pubmed/29081404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101306 |
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