A carregar...
Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase
Mutants of lamin A cause diseases including the Hutchinson-Gilford progeria syndrome (HGPS) characterized by premature aging. Lamin A undergoes a series of processing reactions, including farnesylation and proteolytic cleavage of the farnesylated C-terminal domain. The role of cleavage is unknown bu...
Na minha lista:
| Publicado no: | Aging (Albany NY) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4789588/ https://ncbi.nlm.nih.gov/pubmed/26922519 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|