FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming

Antigen-presenting cells (APCs) such as dendritic cells (DCs) are crucial for initiation of adequate inflammatory responses, which critically depends on the cooperated engagement of different receptors. In addition to pattern recognition receptors (PRRs), Fc gamma receptors (FcγRs) have recently bee...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Hoepel, Willianne, Newling, Melissa, Vogelpoel, Lisa T. C., Sritharan, Lathees, Hansen, Ivo S., Kapsenberg, Martien L., Baeten, Dominique L. P., Everts, Bart, den Dunnen, Jeroen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464031/
https://ncbi.nlm.nih.gov/pubmed/31024565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00739
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