FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming

Antigen-presenting cells (APCs) such as dendritic cells (DCs) are crucial for initiation of adequate inflammatory responses, which critically depends on the cooperated engagement of different receptors. In addition to pattern recognition receptors (PRRs), Fc gamma receptors (FcγRs) have recently bee...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hoepel, Willianne, Newling, Melissa, Vogelpoel, Lisa T. C., Sritharan, Lathees, Hansen, Ivo S., Kapsenberg, Martien L., Baeten, Dominique L. P., Everts, Bart, den Dunnen, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464031/
https://ncbi.nlm.nih.gov/pubmed/31024565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00739
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