Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells

Type I and type III interferons (IFNs) are fundamental for antiviral immunity, but prolonged expression is also detrimental to the host. Therefore, upon viral infection high levels of type I and III IFNs are followed by a strong and rapid decline. However, the mechanisms responsible for this suppres...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Newling, Melissa, Hoepel, Willianne, Vogelpoel, Lisa T.C., Heineke, Marieke H., van Burgsteden, Johan A., Taanman‐Kueter, Esther W.M., Eggink, Dirk, Kuijpers, Taco W., Beaumont, Tim, van Egmond, Marjolein, Kapsenberg, Martien L., Baeten, Dominique L.P., den Dunnen, Jeroen, de Jong, Esther C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Innate immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282563/
https://ncbi.nlm.nih.gov/pubmed/30184252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201847615
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