The RING domain in the anti-apoptotic protein XIAP stabilizes c-Myc protein and preserves anchorage-independent growth of bladder cancer cells

X-linked inhibitor of apoptosis protein (XIAP) suppresses apoptosis and plays key roles in the development, growth, migration, and invasion of cancer cells. Therefore, XIAP has recently attracted much attention as a potential antineoplastic therapeutic target, requiring elucidation of the molecular...

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Vydáno v:J Biol Chem
Hlavní autoři: Jiang, Guosong, Huang, Chao, Liao, Xin, Li, Jingxia, Wu, Xue-Ru, Zeng, Fuqing, Huang, Chuanshu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463729/
https://ncbi.nlm.nih.gov/pubmed/30819803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005621
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