X-linked Inhibitor of Apoptosis Protein (XIAP) Regulation of Cyclin D1 Protein Expression and Cancer Cell Anchorage-independent Growth via Its E3 Ligase-mediated Protein Phosphatase 2A/c-Jun Axis

The X-linked inhibitor of apoptosis protein (XIAP) is a well known potent inhibitor of apoptosis; however, it is also involved in other cancer cell biological behavior. In the current study, we discovered that XIAP and its E3 ligase played a crucial role in regulation of cyclin D1 expression in canc...

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Autors principals: Cao, Zipeng, Zhang, Ruowen, Li, Jingxia, Huang, Haishan, Zhang, Dongyun, Zhang, Jingjie, Gao, Jimin, Chen, Jingyuan, Huang, Chuanshu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711291/
https://ncbi.nlm.nih.gov/pubmed/23720779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.448365
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