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Single-cell quantification of the concentrations and dissociation constants of endogenous proteins

Kinetic simulation is a useful approach for elucidating complex cell-signaling systems. The numerical simulations required for kinetic modeling in live cells critically require parameters such as protein concentrations and dissociation constants (K(d)). However, only a limited number of parameters h...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Komatsubara, Akira T., Goto, Yuhei, Kondo, Yohei, Matsuda, Michiyuki, Aoki, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463716/
https://ncbi.nlm.nih.gov/pubmed/30739083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007685
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