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Zinc transporter 10 (ZnT10)-dependent extrusion of cellular Mn(2+) is driven by an active Ca(2+)-coupled exchange

Manganese (Mn(2+)) is extruded from the cell by the zinc transporter 10 (ZnT10). Loss of ZnT10 expression caused by autosomal mutations in the ZnT10 gene leads to hypermanganesemia in multiple organs. Here, combining fluorescent monitoring of cation influx in HEK293-T cells expressing human ZnT10 wi...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Levy, Moshe, Elkoshi, Nadav, Barber-Zucker, Shiran, Hoch, Eitan, Zarivach, Raz, Hershfinkel, Michal, Sekler, Israel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463715/
https://ncbi.nlm.nih.gov/pubmed/30755481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006816
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