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Identification of the Zn(2+) Binding Site and Mode of Operation of a Mammalian Zn(2+) Transporter
Vesicular zinc transporters (ZnTs) play a critical role in regulating Zn(2+) homeostasis in various cellular compartments and are linked to major diseases ranging from Alzheimer disease to diabetes. Despite their importance, the intracellular localization of ZnTs poses a major challenge for establis...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719407/ https://ncbi.nlm.nih.gov/pubmed/19366695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007203 |
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