Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn(2+) over Cd(2+) selectivity

Por Hoch, Eitan, Lin, Wei, Chai, Jin, Hershfinkel, Michal, Fu, Dax, Sekler, Israel
Publicado em 2012

Identification of the Zn(2+) Binding Site and Mode of Operation of a Mammalian Zn(2+) Transporter

Por Ohana, Ehud, Hoch, Eitan, Keasar, Chen, Kambe, Taiho, Yifrach, Ofer, Hershfinkel, Michal, Sekler, Israel
Publicado em 2009

The PP-motif in luminal loop 2 of ZnT transporters plays a pivotal role in TNAP activation

Por Fujimoto, Shigeyuki, Tsuji, Tokuji, Fujiwara, Takashi, Takeda, Taka-aki, Merriman, Chengfeng, Fukunaka, Ayako, Nishito, Yukina, Fu, Dax, Hoch, Eitan, Sekler, Israel, Fukue, Kazuhisa, Miyamae, Yusaku, Masuda, Seiji, Nagao, Masaya, Kambe, Taiho
Publicado no Biochem J (2016)

Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms

Por Rusu, Victor, Hoch, Eitan, Mercader, Josep M., Tenen, Danielle E., Gymrek, Melissa, Hartigan, Christina R., DeRan, Michael, von Grotthuss, Marcin, Fontanillas, Pierre, Spooner, Alexandra, Guzman, Gaelen, Deik, Amy A., Pierce, Kerry A., Dennis, Courtney, Clish, Clary B., Carr, Steven A., Wagner, Bridget K., Schenone, Monica, Ng, Maggie C.Y., Chen, Brian H., Centeno-Cruz, Federico, Zerrweck, Carlos, Orozco, Lorena, Altshuler, David M., Schreiber, Stuart L., Florez, Jose C., Jacobs, Suzanne B. R., Lander, Eric S.
Publicado no Cell (2017)