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Cideb controls sterol‐regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites

SREBPs are master regulators of lipid homeostasis and undergo sterol‐regulated export from ER to Golgi apparatus for processing and activation via COPII‐coated vesicles. While COPII recognizes SREBP through its escort protein SCAP, factor(s) specifically promoting SREBP/SCAP loading to the COPII mac...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Su, Lu, Zhou, Linkang, Chen, Feng‐Jung, Wang, Huimin, Qian, Hui, Sheng, Yuanyuan, Zhu, Yuangang, Yu, Hua, Gong, Xinqi, Cai, Li'e, Yang, Xuerui, Xu, Li, Zhao, Tong‐Jin, Li, John Zhong, Chen, Xiao‐Wei, Li, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463267/
https://ncbi.nlm.nih.gov/pubmed/30858281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100156
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