Cideb controls sterol‐regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites

SREBPs are master regulators of lipid homeostasis and undergo sterol‐regulated export from ER to Golgi apparatus for processing and activation via COPII‐coated vesicles. While COPII recognizes SREBP through its escort protein SCAP, factor(s) specifically promoting SREBP/SCAP loading to the COPII mac...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Su, Lu, Zhou, Linkang, Chen, Feng‐Jung, Wang, Huimin, Qian, Hui, Sheng, Yuanyuan, Zhu, Yuangang, Yu, Hua, Gong, Xinqi, Cai, Li'e, Yang, Xuerui, Xu, Li, Zhao, Tong‐Jin, Li, John Zhong, Chen, Xiao‐Wei, Li, Peng
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463267/
https://ncbi.nlm.nih.gov/pubmed/30858281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100156
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