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Cideb controls sterol‐regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites
SREBPs are master regulators of lipid homeostasis and undergo sterol‐regulated export from ER to Golgi apparatus for processing and activation via COPII‐coated vesicles. While COPII recognizes SREBP through its escort protein SCAP, factor(s) specifically promoting SREBP/SCAP loading to the COPII mac...
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| 發表在: | EMBO J |
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| Main Authors: | , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6463267/ https://ncbi.nlm.nih.gov/pubmed/30858281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100156 |
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