Cideb controls sterol‐regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites

SREBPs are master regulators of lipid homeostasis and undergo sterol‐regulated export from ER to Golgi apparatus for processing and activation via COPII‐coated vesicles. While COPII recognizes SREBP through its escort protein SCAP, factor(s) specifically promoting SREBP/SCAP loading to the COPII mac...

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Vydáno v:EMBO J
Hlavní autoři: Su, Lu, Zhou, Linkang, Chen, Feng‐Jung, Wang, Huimin, Qian, Hui, Sheng, Yuanyuan, Zhu, Yuangang, Yu, Hua, Gong, Xinqi, Cai, Li'e, Yang, Xuerui, Xu, Li, Zhao, Tong‐Jin, Li, John Zhong, Chen, Xiao‐Wei, Li, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463267/
https://ncbi.nlm.nih.gov/pubmed/30858281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100156
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