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Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells

Chronic lymphocytic leukemia cells (CLL) migrate between the blood and lymphoid tissues in response to chemokines. Such migration requires structured cytoskeletal-actin polymerization, which may involve the protein cortactin. We discovered that treatment of CLL cells with Wnt5a causes Receptor tyosi...

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Podrobná bibliografie
Vydáno v:Leukemia
Hlavní autoři: Hasan, Md Kamrul, Rassenti, Laura, Widhopf, George F., Yu, Jian, Kipps, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462876/
https://ncbi.nlm.nih.gov/pubmed/30568170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0306-7
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