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Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells

Chronic lymphocytic leukemia cells (CLL) migrate between the blood and lymphoid tissues in response to chemokines. Such migration requires structured cytoskeletal-actin polymerization, which may involve the protein cortactin. We discovered that treatment of CLL cells with Wnt5a causes Receptor tyosi...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Hasan, Md Kamrul, Rassenti, Laura, Widhopf, George F., Yu, Jian, Kipps, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462876/
https://ncbi.nlm.nih.gov/pubmed/30568170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0306-7
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