Shear stress and platelet‐induced tensile forces regulate ADAMTS13‐localization within the platelet thrombus

BACKGROUND: The multimeric glycoprotein von Willebrand factor (VWF) mediates platelet adhesion and aggregation at the site of vessel injury. The adhesive activity of VWF is influenced by its multimer length which is regulated by the metalloprotease ADAMTS13. The ability of ADAMTS13 to regulate plate...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Res Pract Thromb Haemost
Päätekijät: Shida, Yasuaki, Swystun, Laura L., Brown, Christine, Mewburn, Jeffrey, Nesbitt, Kate, Danisment, Ozge, Riches, Jonathan Jacob, Hough, Christine, Lillicrap, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Original Articles: Haemostasis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462754/
https://ncbi.nlm.nih.gov/pubmed/31011709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12196
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