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Novel Stenotic Microchannels to Study Thrombus Formation in Shear Gradients: Influence of Shear Forces and Human Platelet-Related Factors

Thrombus formation in hemostasis or thrombotic disease is initiated by the rapid adhesion, activation, and aggregation of circulating platelets in flowing blood. At arterial or pathological shear rates, for example due to vascular stenosis or circulatory support devices, platelets may be exposed to...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lui, Mathew, Gardiner, Elizabeth E., Arthur, Jane F., Pinar, Isaac, Lee, Woei Ming, Ryan, Kris, Carberry, Josie, Andrews, Robert K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627598/
https://ncbi.nlm.nih.gov/pubmed/31216638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20122967
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