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Mitochondrial proteostasis in the context of cellular and organismal health and aging
As a central hub of cellular metabolism and signaling, the mitochondrion is a crucial organelle whose dysfunction can cause disease and whose activity is intimately connected to aging. We review how the mitochondrial network maintains proteomic integrity, how mitochondrial proteotoxic stress is comm...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462515/ https://ncbi.nlm.nih.gov/pubmed/29622680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM117.000893 |
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