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Mediation of organismal aging and somatic proteostasis by the germline

Experimental interventions that reduce reproduction cause an extension in lifespan. In invertebrates, such as Caenorhabditis elegans, the aging of the soma is regulated by signals from the germline. Indeed, ablation of germ cells significantly extends lifespan. Notably, germline-deficient animals ex...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Khodakarami, Amirabbas, Saez, Isabel, Mels, Johanna, Vilchez, David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428440/
https://ncbi.nlm.nih.gov/pubmed/25988171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00003
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