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Mediation of organismal aging and somatic proteostasis by the germline
Experimental interventions that reduce reproduction cause an extension in lifespan. In invertebrates, such as Caenorhabditis elegans, the aging of the soma is regulated by signals from the germline. Indeed, ablation of germ cells significantly extends lifespan. Notably, germline-deficient animals ex...
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| Udgivet i: | Front Mol Biosci |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428440/ https://ncbi.nlm.nih.gov/pubmed/25988171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00003 |
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