Targeting Notch1 and IKKα enhanced NF-κB activation in CD133(+) Skin Cancer Stem Cells

Cancer stem-like cells are hypothesized to be the major tumor initiating cell population of human cutaneous squamous cell carcinoma (cSCC), but the landscape of molecular alterations underpinning their signaling and cellular phenotypes as drug targets remain undefined. In this study, we developed an...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Quan, Xin Xin, Hawk, Nga Voong, Chen, Weiping, Coupar, Jamie, Lee, Steven, Petersen, David W, Meltzer, Paul S, Montemarano, Andrew, Braun, Martin, Chen, Zhong, Van Waes, Carter
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461743/
https://ncbi.nlm.nih.gov/pubmed/29959199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0421
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