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TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn

Ten-eleven-translocation (TET) proteins catalyze DNA hydroxylation, playing an important role in demethylation of DNA in mammals. Remarkably, although hydroxymethylation levels are high in the mouse brain, the potential role of TET proteins in adult neurogenesis is unknown. We show here that a non-c...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Montalbán-Loro, Raquel, Lozano-Ureña, Anna, Ito, Mitsuteru, Krueger, Christel, Reik, Wolf, Ferguson-Smith, Anne C., Ferrón, Sacri R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461695/
https://ncbi.nlm.nih.gov/pubmed/30979904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09665-1
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