Single-chain Tet transregulators
We demonstrate here that the Tet repressor (TetR), a dimeric allosterical regulatory protein, can be converted to a fully functional monomer when connected by a 29 amino acid linker. TetR-based transregulators are widely used to regulate gene expression in eukaryotes. They can be fused to form singl...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12799431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg421 |
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