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TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn

Ten-eleven-translocation (TET) proteins catalyze DNA hydroxylation, playing an important role in demethylation of DNA in mammals. Remarkably, although hydroxymethylation levels are high in the mouse brain, the potential role of TET proteins in adult neurogenesis is unknown. We show here that a non-c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Montalbán-Loro, Raquel, Lozano-Ureña, Anna, Ito, Mitsuteru, Krueger, Christel, Reik, Wolf, Ferguson-Smith, Anne C., Ferrón, Sacri R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461695/
https://ncbi.nlm.nih.gov/pubmed/30979904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09665-1
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