Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability

Genomic imprinting is important for normal brain development and aberrant imprinting has been associated with impaired cognition. We studied the imprinting status in selected imprints (H19, IGF2, SNRPN, PEG3, MEST1, NESPAS, KvDMR, IG-DMR and ZAC1) by pyrosequencing in blood samples from longitudinal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lorgen-Ritchie, Marlene, Murray, Alison D., Ferguson-Smith, Anne C., Richards, Marcus, Horgan, Graham W., Phillips, Louise H., Hoad, Gwen, Gall, Ishbel, Harrison, Kristina, McNeill, Geraldine, Ito, Mitsuteru, Haggarty, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358095/
https://ncbi.nlm.nih.gov/pubmed/30707743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211799
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