Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability

Genomic imprinting is important for normal brain development and aberrant imprinting has been associated with impaired cognition. We studied the imprinting status in selected imprints (H19, IGF2, SNRPN, PEG3, MEST1, NESPAS, KvDMR, IG-DMR and ZAC1) by pyrosequencing in blood samples from longitudinal...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Lorgen-Ritchie, Marlene, Murray, Alison D., Ferguson-Smith, Anne C., Richards, Marcus, Horgan, Graham W., Phillips, Louise H., Hoad, Gwen, Gall, Ishbel, Harrison, Kristina, McNeill, Geraldine, Ito, Mitsuteru, Haggarty, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358095/
https://ncbi.nlm.nih.gov/pubmed/30707743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211799
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