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Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

ATP-dependent chromatin remodelling enzymes (remodellers) regulate DNA accessibility in eukaryotic genomes. Many remodellers reposition (slide) nucleosomes, however, how DNA is propagated around the histone octamer during this process is unclear. Here we examine the real-time coordination of remodel...

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Pubblicato in:Nat Commun
Autori principali: Sabantsev, Anton, Levendosky, Robert F., Zhuang, Xiaowei, Bowman, Gregory D., Deindl, Sebastian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461674/
https://ncbi.nlm.nih.gov/pubmed/30979890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09657-1
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