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Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

ATP-dependent chromatin remodelling enzymes (remodellers) regulate DNA accessibility in eukaryotic genomes. Many remodellers reposition (slide) nucleosomes, however, how DNA is propagated around the histone octamer during this process is unclear. Here we examine the real-time coordination of remodel...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sabantsev, Anton, Levendosky, Robert F., Zhuang, Xiaowei, Bowman, Gregory D., Deindl, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461674/
https://ncbi.nlm.nih.gov/pubmed/30979890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09657-1
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