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Asymmetry between the two acidic patches dictates the direction of nucleosome sliding by the ISWI chromatin remodeler

The acidic patch is a functionally important epitope on each face of the nucleosome that affects chromatin remodeling. Although related by 2-fold symmetry of the nucleosome, each acidic patch is uniquely positioned relative to a bound remodeler. An open question is whether remodelers are distinctly...

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Bibliographic Details
Published in:eLife
Main Authors: Levendosky, Robert F, Bowman, Gregory D
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546392/
https://ncbi.nlm.nih.gov/pubmed/31094676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45472
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