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Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

ATP-dependent chromatin remodelling enzymes (remodellers) regulate DNA accessibility in eukaryotic genomes. Many remodellers reposition (slide) nucleosomes, however, how DNA is propagated around the histone octamer during this process is unclear. Here we examine the real-time coordination of remodel...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Sabantsev, Anton, Levendosky, Robert F., Zhuang, Xiaowei, Bowman, Gregory D., Deindl, Sebastian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461674/
https://ncbi.nlm.nih.gov/pubmed/30979890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09657-1
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