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Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA
ISWI-family remodelling enzymes regulate access to genomic DNA by mobilizing nucleosomes(1). These ATP-dependent chromatin remodellers promote heterochromatin formation and transcriptional silencing(1) by generating regularly-spaced nucleosome arrays(2-5). The nucleosome-spacing activity arises from...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134374/ https://ncbi.nlm.nih.gov/pubmed/25043036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13380 |
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