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Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA

ISWI-family remodelling enzymes regulate access to genomic DNA by mobilizing nucleosomes(1). These ATP-dependent chromatin remodellers promote heterochromatin formation and transcriptional silencing(1) by generating regularly-spaced nucleosome arrays(2-5). The nucleosome-spacing activity arises from...

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Sonraí Bibleagrafaíochta
Main Authors: Hwang, William L., Deindl, Sebastian, Harada, Bryan T., Zhuang, Xiaowei
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134374/
https://ncbi.nlm.nih.gov/pubmed/25043036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13380
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