Pancreatitis-Induced Depletion of Syntaxin 2 Promotes Autophagy and Increases Basolateral Exocytosis

BACKGROUND & AIMS: Pancreatic acinar cells are polarized epithelial cells that store enzymes required for digestion as inactive zymogens, tightly packed at the cell apex. Stimulation of acinar cells causes the zymogen granules to fuse with the apical membrane, and the cells undergo exocytosis to...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Dolai, Subhankar, Liang, Tao, Orabi, Abrahim I., Holmyard, Douglas, Xie, Li, Greitzer-Antes, Dafna, Kang, Youhou, Xie, Huanli, Javed, Tanveer A., Lam, Patrick P., Rubin, Deborah C., Thorn, Peter, Gaisano, Herbert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461447/
https://ncbi.nlm.nih.gov/pubmed/29360461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.01.025
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