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Pancreatitis-Induced Depletion of Syntaxin 2 Promotes Autophagy and Increases Basolateral Exocytosis

BACKGROUND & AIMS: Pancreatic acinar cells are polarized epithelial cells that store enzymes required for digestion as inactive zymogens, tightly packed at the cell apex. Stimulation of acinar cells causes the zymogen granules to fuse with the apical membrane, and the cells undergo exocytosis to...

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Foilsithe in:Gastroenterology
Main Authors: Dolai, Subhankar, Liang, Tao, Orabi, Abrahim I., Holmyard, Douglas, Xie, Li, Greitzer-Antes, Dafna, Kang, Youhou, Xie, Huanli, Javed, Tanveer A., Lam, Patrick P., Rubin, Deborah C., Thorn, Peter, Gaisano, Herbert Y.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461447/
https://ncbi.nlm.nih.gov/pubmed/29360461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.01.025
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