Treadmill Exercise Decreases Aβ Deposition and Counteracts Cognitive Decline in APP/PS1 Mice, Possibly via Hippocampal Microglia Modifications

Recent studies have suggested that exercise may be beneficial for delaying or attenuating Alzheimer’s disease (AD). However, the underlying mechanisms were not clear. Microglia-mediated neuroinflammation is suggested to play an important role in the pathology of AD. The present study investigated th...

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Опубликовано в: :Front Aging Neurosci
Главные авторы: Zhang, Xianliang, He, Qiang, Huang, Tao, Zhao, Na, Liang, Fei, Xu, Bo, Chen, Xianghe, Li, Tuojian, Bi, Jianzhong
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461026/
https://ncbi.nlm.nih.gov/pubmed/31024293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00078
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