Treadmill Exercise Decreases Aβ Deposition and Counteracts Cognitive Decline in APP/PS1 Mice, Possibly via Hippocampal Microglia Modifications

Recent studies have suggested that exercise may be beneficial for delaying or attenuating Alzheimer’s disease (AD). However, the underlying mechanisms were not clear. Microglia-mediated neuroinflammation is suggested to play an important role in the pathology of AD. The present study investigated th...

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Bibliografiske detaljer
Udgivet i:Front Aging Neurosci
Main Authors: Zhang, Xianliang, He, Qiang, Huang, Tao, Zhao, Na, Liang, Fei, Xu, Bo, Chen, Xianghe, Li, Tuojian, Bi, Jianzhong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461026/
https://ncbi.nlm.nih.gov/pubmed/31024293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00078
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