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Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice
Surgery can induce cognitive decline, a risk that increases with advancing age. In rodents, postoperative cognitive decline (POCD) is associated with the inflammatory activation of hippocampal microglia. To examine the role of microglia in POCD, we inhibited the colony-stimulating factor 1 receptor...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374063/ https://ncbi.nlm.nih.gov/pubmed/28405620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91229 |
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