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Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice
Surgery can induce cognitive decline, a risk that increases with advancing age. In rodents, postoperative cognitive decline (POCD) is associated with the inflammatory activation of hippocampal microglia. To examine the role of microglia in POCD, we inhibited the colony-stimulating factor 1 receptor...
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| Pubblicato in: | JCI Insight |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374063/ https://ncbi.nlm.nih.gov/pubmed/28405620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91229 |
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