Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice

Surgery can induce cognitive decline, a risk that increases with advancing age. In rodents, postoperative cognitive decline (POCD) is associated with the inflammatory activation of hippocampal microglia. To examine the role of microglia in POCD, we inhibited the colony-stimulating factor 1 receptor...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Feng, Xiaomei, Valdearcos, Martin, Uchida, Yosuke, Lutrin, David, Maze, Mervyn, Koliwad, Suneil K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374063/
https://ncbi.nlm.nih.gov/pubmed/28405620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91229
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