Benzo(a)pyrene exposure induced neuronal loss, plaque deposition, and cognitive decline in APP/PS1 mice

BACKGROUND: Exposure to benzo(a)pyrene (BaP) was associated with cognitive impairments and some Alzheimer’s disease (AD)-like pathological changes. However, it is largely unknown whether BaP exposure participates in the disease progression of AD. OBJECTIVES: To investigate the effect of BaP exposure...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Liu, Dan, Zhao, Yujia, Qi, Yuze, Gao, Yun, Tu, Dezhen, Wang, Yinxi, Gao, Hui-Ming, Zhou, Hui
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461337/
https://ncbi.nlm.nih.gov/pubmed/32867800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01925-y
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