Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer’s disease mice

BACKGROUND: There is increasing interest in whether anesthetic agents affect the risk or progression of Alzheimer’s disease (AD). To mitigate many of the methodological issues encountered in human retrospective cohort studies we have used a transgenic model of AD to investigate the effect of propofo...

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Udgivet i:BMC Anesthesiol
Main Authors: Woodhouse, Adele, Fernandez-Martos, Carmen Maria, Atkinson, Rachel Alice Kathryn, Hanson, Kelsey Anne, Collins, Jessica Marie, O’Mara, Aidan Ryan, Terblanche, Nico, Skinner, Marcus Welby, Vickers, James Clement, King, Anna Elizabeth
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921792/
https://ncbi.nlm.nih.gov/pubmed/29699479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-018-0509-5
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