Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer’s disease mice

BACKGROUND: There is increasing interest in whether anesthetic agents affect the risk or progression of Alzheimer’s disease (AD). To mitigate many of the methodological issues encountered in human retrospective cohort studies we have used a transgenic model of AD to investigate the effect of propofo...

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Veröffentlicht in:BMC Anesthesiol
Hauptverfasser: Woodhouse, Adele, Fernandez-Martos, Carmen Maria, Atkinson, Rachel Alice Kathryn, Hanson, Kelsey Anne, Collins, Jessica Marie, O’Mara, Aidan Ryan, Terblanche, Nico, Skinner, Marcus Welby, Vickers, James Clement, King, Anna Elizabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921792/
https://ncbi.nlm.nih.gov/pubmed/29699479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-018-0509-5
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