Fluoxetine Promotes Hippocampal Oligodendrocyte Maturation and Delays Learning and Memory Decline in APP/PS1 Mice

Oligodendrogenesis dysfunction impairs memory consolidation in adult mice, and an oligodendrocyte abnormality is an important change occurring in Alzheimer's disease (AD). While fluoxetine (FLX) is known to delay memory decline in AD models, its effects on hippocampal oligodendrogenesis are unc...

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Bibliografische gegevens
Gepubliceerd in:Front Aging Neurosci
Hoofdauteurs: Chao, Feng-lei, Zhang, Yi, Zhang, Lei, Jiang, Lin, Zhou, Chun-ni, Tang, Jing, Liang, Xin, Fan, Jin-hua, Dou, Xiao-yun, Tang, Yong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838348/
https://ncbi.nlm.nih.gov/pubmed/33519426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.627362
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