Novel Approach to Cell Surface Discrimination Between KIR2DL1 Subtypes and KIR2DS1 Identifies Hierarchies in NK Repertoire, Education, and Tolerance

Cumulative activating and inhibitory receptor signaling controls the functional output of individual natural killer (NK) cells. Investigation of how competing signals impact response, however, has been hampered by the lack of available antibodies capable of distinguishing inhibitory and activating r...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Le Luduec, Jean-Benoît, Boudreau, Jeanette E., Freiberg, Julian C., Hsu, Katharine C.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460669/
https://ncbi.nlm.nih.gov/pubmed/31024561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00734
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