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Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice
Mice deficient in SHANK-associated RH domain-interacting protein (SHARPIN), a component of the linear ubiquitin chain assembly complex (LUBAC), develop a spontaneous inflammatory disorder with pathologic hallmarks similar to atopic dermatitis and psoriasis in humans. Previous studies identified the...
Tallennettuna:
| Julkaisussa: | Cell Death Differ |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6460383/ https://ncbi.nlm.nih.gov/pubmed/30038386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0159-7 |
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