A carregar...
SYK licenses MyD88 to instigate IL-1α-mediated inflammatory disease
Mice carrying a hypomorphic point mutation in the Ptpn6 gene (Ptpn6(spin) mice) develop an inflammatory skin disease that resembles neutrophilic dermatosis in humans. Here, we demonstrated that interleukin (IL)-1α signaling through IL-1R and MyD88 in both stromal and immune cells drive inflammation...
Na minha lista:
| Publicado no: | Immunity |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501252/ https://ncbi.nlm.nih.gov/pubmed/28410990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.03.014 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|