A carregar...
A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers
Cohesin is a multiprotein ring that is responsible for cohesion of sister chromatids and formation of DNA loops to regulate gene expression. Genomic analyses have identified that the cohesin subunit STAG2 is frequently inactivated by mutations in cancer. However, the reason STAG2 mutations are selec...
Na minha lista:
| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6459917/ https://ncbi.nlm.nih.gov/pubmed/30975996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09659-z |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|