DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA

We identified 29 G-quadruplex binding proteins by affinity purification and quantitative LC-MS/MS. We demonstrated that the DEAD-box RNA helicases Dbp2, Ded1 and Mss116 preferentially bind to G-quadruplex nucleic acids in vitro and destabilize RNA quadruplexes, suggesting new potential roles for the...

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Vydáno v:Chem Commun (Camb)
Hlavní autoři: Gao, Jun, Byrd, Alicia K., Zybailov, Boris L., Marecki, John C., Guderyon, Michael J., Edwards, Andrea D., Chib, Shubeena, West, Kirk L., Waldrip, Zachary J., Mackintosh, Samuel G., Gao, Zhaofeng, Putnam, Andrea A., Jankowsky, Eckhard, Raney, Kevin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459694/
https://ncbi.nlm.nih.gov/pubmed/30855040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc10091h
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