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Synthesis of Phthalans Via Copper-Catalyzed Enantioselective Cyclization/Carboetherification of 2-Vinylbenzyl Alcohols

Enantiomerically enriched phthalans were synthesized efficiently via an enantioselective copper-catalyzed alkene carboetherification reaction. In this reaction, 2-vinylbenzyl alcohols enantioselectively cyclize then couple with vinylarenes. The utility of the method was demonstrated by the enantiose...

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Vydáno v:Org Lett
Hlavní autoři: Chen, Dake, Chemler, Sherry R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459690/
https://ncbi.nlm.nih.gov/pubmed/30336677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b02766
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